Assessment of Postprandial Abdominal Fullness in Patients after Pylorus-Preserving Gastrectomy for Early Gastric Cancer

Abstract

1. Abstract 1.1. <span style=font-size:10.0pt;font-family: times= new= roman,serif;color:black=>Background: To assess Postprandial Abdominal Fullness (PAF) in Pylorus-Preserving Gastrectomy (PPG) patients, the author investigated relationships between PAF and Postgastrectomy Disorder (PGD) and Gastric Empting Function (GEF). 1.2. <span style=font-size:10.0pt;font-family: times= new= roman,serif;color:black=>Methods: A total of 22 patients 1 year after PPG for early gastric cancer were divided into 2 groups [Group A, PAF- positive (n=12); Group B, PAF-negative (n=10)]. The relationships among PAF, PGD, and GEF were studied. 1.3. <span style=font-size:10.0pt;font-family: times= new= roman,serif;color:black=>Results: The Length of The Antral Cuff (LAC) was significantly shorter in group A than in group B (p=0.0245). Appetite and food consumption per meal were significantly more favorable in group B than in group A (p=0.0202, p=0.0082, respectively). Symptomatic Reflux Esophagitis (RE), early dumping syndrome, decreased percent body weight preillness, endoscopic RE and endoscopic gastritis in the remnant stomach were more frequent in group A than in group B. Gastric stasis in the remnant stomach was significantly more frequent in group A than in group B (p=0.0071). GEF with the solid diet in group A was significantly more delayed than in group B (p=0.0001). There was no significant difference in GEF with the liquid diet in either group. 1.4. <span style=font-size:10.0pt;font-family: times= new= roman,serif;color:black=>Conclusions: Patients with PAF showed a short LAC, delayed GEF with the solid diet, and a more unfavorable postoperative QOL compared with those without PAF. <span style=font-size:11.0pt; font-family: times= new= roman,serif;mso-fareast-font-family:平成明朝;color:black;= mso-ansi-language:en-us;mso-fareast-language:ja;mso-bidi-language:ar-sa;= mso-no-proof:yes=>Keywords: <span style=font-size:10.0pt; font-family: times= new= roman,serif;mso-fareast-font-family:平成明朝;color:black;= mso-ansi-language:en-us;mso-fareast-language:ja;mso-bidi-language:ar-sa;= mso-no-proof:yes=>Early Gastric Cancer; Gastric Empting Function; Postgastrectomy Disorder; Postprandial Abdominal Fullness; Pylorus-Preserving Gastrectomy