Assessment of post-infarct ventricular septal defects through 3D printing and statistical shape analysis.

Abstract

Post-infarct ventricular septal defect (PIVSD) is a serious complication of myocardial infarction. We evaluated 3D-printing models in PIVSD clinical assessment and the feasibility of statistical shape modeling for morphological analysis of the defects. Models (n=15) reconstructed from computed tomography data were evaluated by clinicians (n=8). Statistical shape modeling was performed on 3D meshes to calculate the mean morphological configuration of the defects. Clinicians' evaluation highlighted the models' utility in displaying defects for interventional/surgical planning, education/training and device development. However, models lack dynamic representation. Morphological analysis was feasible and revealed oval-shaped (n=12) and complex channel-like (n=3) defects. 3D-PIVSD models can complement imaging data for teaching and procedural planning. Statistical shape modeling is feasible in this scenario.