Assessment of peri-implant tissue dimensions following surgical therapy of advanced ligature-induced peri-implantitis defects

Ausra Ramanauskaite,Frank Schwarz,Jürgen Becker,Robert Sader,Karina Obreja

doi:10.1186/s40729-020-00282-y

Abstract

BackgroundTo evaluate peri-implant tissue dimensions following implantoplasty and/or regenerative therapy of advanced ligature-induced peri-implantitis in dogs.Material and methodsAt all defect sites (n = 6 dogs, n = 48 implants), the intrabony component was filled with a particulate bovine-derived natural bone mineral (NBM). The supracrestal component was treated by either the application of an equine bone block (EB) or implantoplasty. In a split-mouth design, NBM and EB were soak-loaded with rhBMP-2 or sterile saline. All sites were covered using a native collagen membrane and left to heal in a submerged position for 12 weeks. The horizontal mucosal thickness (hMT) and bone thickness (hBT) were measured at four reference points: (v0) at the level of implant shoulder (IS), (v1) 50% of the distance IS-bone crest (BC), (v2) at the BC, and (v3) at the most coronal extension of the bone-to-implant contact.ResultsThe general tendency indicated a gradual increase in hMT from the IS (v0) toward BC (v2), which was more pronounced at implant sites treated with the regenerative approach. The hBT values increased from v2 to v3, with the highest values at the v3 region measured for implant sites treated with adjunctive rhBMP-2. For sites treated with implantoplasty, the linear regression model demonstrated an inverse correlation between hMT and hBT, whereas a positive correlation was observed at those sites treated with the regenerative approach.ConclusionHorizontal soft and hard tissue dimensions were similar among different treatment groups.

Highlights

Due to a high prevalence, the management of periimplantitis has become a common issue in daily clinical practice [1]
The general tendency indicated a gradual increase in horizontal mucosal thickness (hMT) from the implant shoulder (IS) (v0) toward bone crest (BC) (v2), which was more pronounced at implant sites treated with the regenerative approach
For sites treated with implantoplasty, the linear regression model demonstrated an inverse correlation between hMT and hBT, whereas a positive correlation was observed at those sites treated with the regenerative approach

Summary

Introduction

Due to a high prevalence, the management of periimplantitis has become a common issue in daily clinical practice [1]. While non-surgical approaches have shown limited clinical outcomes, surgical techniques with or without adjunctive resective and/or augmentative measures tended to be associated with a higher efficacy in reducing. Even though adjunctive augmentative measures have been shown to enhance radiographic bone levels over non-augmentative techniques, they failed to reduce the postoperative occurrence of mucosal recessions Horizontal peri-implant mucosal thickness, called biotype, was suggested to affect the occurrence of soft-tissue recession. Due to the inflammatory lesion and associated increase in mucosal thickness, the assessment of the biotype is challenging at periimplantitis sites [13]. It appears to be reasonable that the aforementioned changes in peri-implant soft tissue level following surgical therapy of periimplantitis may be mainly due to the resolution of the inflammatory lesion rather than a trauma caused by the intervention. To evaluate peri-implant tissue dimensions following implantoplasty and/or regenerative therapy of advanced ligature-induced peri-implantitis in dogs

Methods

Results

Conclusion