ASSESSMENT OF PATHOLOGICAL CHANGE OF SCHISTOSOMA MANSONI INFECTIONIN THE LIVER USING ULTRASOUNOGRAPHY

Abdal Gadir Yonis,Al Safi Ahmed Abdallash,Ashraf Mustafa Mohammed Osman,Mona Ahmed

doi:10.29121/granthaalayah.v7.i7.2019.738

Abstract

Background: Schistosomiasis is a tropical parasitic disease caused by blood flukes of the genus Schistosoma, causes periportal fibrosis and portal hypertension in approximately 13%-18% of those afflicted with the disease in the Gezira irrigated areas of Sudan. This a prospective study compromise of 360 consecutive patients at North Gezira State between 2016 to 2019 aimed to assessment of pathological change in schistosomiasismansoni infection using B-mode grayscale ultrasound, The images done by portable Sono Scape- A6 machine using convex probe with frequency range from 3.5 to 5 MHz and the data analyzed by SPSS version 15. The result showed that the majority of patients were male and periportal fibrosis had high incidence associated with schistosomiasismansoni, Out of 360 patients with schistosomal PPF under study there were no PPF noted in 56 (15.6%) , while the remaining had mild in106 (29.4%), moderate in166 (46.1%), and severe PPF in 32 (8,9%) The study concluded that the B- mode Gray scale portable ultrasound machine is the most frequently used imaging modality to assess patients for the presence of periportalfibrosis especially in the endemic area.

Highlights

This is a prospective study aimed to assessment of pathological change in schistosomiasismansoni infection used B-mode grayscale ultrasound, compromise of 360,56 patients have normal liver,198 patients have periportal fibrosis with portal hypertension, and 106 patients have periportal fibrosis .carried out in the period from january2016 to 2019 in north Gazira state in Sudan and private clinic at Gebel Awlia Khartoum state. requested abdominal US was done with prior explanation of the investigation and informed written consent of the patients .ultrasound done was performed on SonoScape- A6 portable machine using convex probe with frequency range from 3.5 to 5 MHz liver was scanned in various planes like transverse, sagittal, sub costal, obliqueinter costals and coronal planes
This study found patients in age between 30 to80 years distribution were mostly in [50-60]years forming the incidence of 33.6% [121]patient, in[40-55]years 28.6% [103]patients table[2].This study was used for both diagnosis and grading of periportal fibrosis .Grading was allotted this grades by modification of the original method described by Safaa
Out of 360 patients with schistosomal PPF under study there were no PPF noted in 56(15.6%), while the remaining had mild in106 (29.4%), moderate in166 (46.1%), and severe PPF in 32(8,9%) table[3].The 29.4%of patient not a percentage, because It is important not to limit cases recorded as positive for periportal fibrosis to those where ultrasound examination reveals pathlogical changes unequivocally

Summary

Background

Schistosomiasis is a tropical parasitic disease caused by blood flukes of the genus Schistosoma, causes periportal fibrosis and portal hypertension in approximately 13%-18% of those afflicted with the disease in the Gezira irrigated areas of Sudan This a prospective study compromise of 360 consecutive patients at North Gezira State between 2016 to 2019 aimed to assessment of pathological change in schistosomiasismansoni infection using B-mode grayscale ultrasound, The images done by portable Sono Scape- A6 machine using convex probe with frequency range from 3.5 to 5 MHz and the data analyzed by SPSS version 15.

Introduction

Material and Methods

Results

Discussion