Assessment of Non-Compliance of Medicine and its Associated Factors among Type II Diabetes Mellitus in a Tertiary Hospital

Abstract

Background: Diabetes mellitus is a devastating disease worldwide, and its impact on human life is alarming. Medication non-compliance is a major cause leading to serious complications and a high burden on the entire healthcare system. Objective: To assess the non-compliance of Medicine and its associated factors in type-II Diabetes mellitus. Methodology: A cross-sectional study was conducted between February 2019 and August 2019 among patients with type 2 diabetes mellitus at the Endocrinology OPD of Dow Hospital Karachi. The Moriskey Medication Adherence Questionnaire-8 was used to assess non-compliance. A non-probability purposive technique was used for data collection, and all patients diagnosed with type II diabetes mellitus were included in this study. Result: 196 participants took part in the study. Most of the participants were male (57.7%), married (85.2%), and over 50 years old (39.3%). The study found that 11.2% of participants had high compliance with medication, while 19.9% had medium adherence and 68.9% had low compliance. In univariate analysis, younger age, presence of comorbid, and prescription of tablets were associated with a lower risk of low/moderate non-compliance. On multivariable analysis, having comorbidity and advice of tablets were found to be associated with lower odds of low to moderate levels of non-adherence. Conclusion: The findings of this study highlight the need to identify the value of measuring patient compliance to treatment plans related to diabetes for the maintenance and co-management of this disease.