Abstract

Evidence suggests that migraine is associated with metabolic syndrome (MetS). We aimed to assess the components of MetS in patients with migraine in Yozgat region known as central Anatolia. Forty-two migraine patients and age- and sex-matched 40 control subjects were enrolled in the study. Migraine diagnosis was settled according to the International Classification of Headache Disorders-II diagnostic criteria. The patients’ blood pressures and waist circumferences (WC) were measured. Body mass index (BMI) was calculated as well as fasting glucose (FG) and lipid profiles were carried out for each patient. BMI, WC and blood pressure measurements were significantly higher in migraine patients than in controls (p < 0.05). FG and Triglycerides were significantly higher in migraineurs as compared to the controls (p < 0.001). The diagnosis of MetS was significantly higher in patients with migraine than in controls (p = 0.001). Attack frequency was significantly lower in migraineurs with MetS than without MetS (p < 0.05). Attack severity and duration were positively correlated with BMI and WC in migraine patients (p < 0.05). The present findings may suggest that MetS and its components were associated with migraine.

Highlights

  • Migraine is a chronic disorder with complex pathophysiology involving neuronal and vascular mechanisms

  • We aimed to assess the components of Metabolic syndrome (MetS) in patients with migraine in Yozgat region known as central Anatolia

  • The measurements of Body mass index (BMI), waist circumferences (WC), Systolic blood pressure (SBP), diastolic blood pressure (DBP) were significantly higher in migraine patients than in controls (p

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Summary

Introduction

Migraine is a chronic disorder with complex pathophysiology involving neuronal and vascular mechanisms. Especially with aura, and vascular disorders such as coronary heart disease and stroke has been reported in previous studies [1]. Obesity and diabetes are metabolic disorders which have a complex association with migraine [2,3]. The relationship between migraine and MetS is still obscure. Several studies suggest that obesity and migraine may be directly linked [3,4,5]. Other studies failed to find any association between migraine and obesity [6,7].

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