ASSESSMENT OF MARKERS OF ALLERGY AND INFLAMMATION IN THE BLOOD OF DOGS WITH FOLLICULAR CYST OF THE INTERDIGITAL SKIN, WITH LOCAL AND GENERALIZED DERMATOLOGICAL REACTION

Abstract

Follicular cyst of the interdigital skin is a common problem in dogs, which causes significant economic damage to service, sports and decorative dog breeding. In the treatment of animals with this pathology, along with surgical intervention, it is necessary to use anti-inflammatory and/or immunosuppressive drugs. Thus, the question arises of studying the intensity of the inflammatory process in dogs with follicular cyst of the interdigital skin. The article presents the results of a study of markers of inflammation and allergy in these animals, including animals with a generalized dermatological reaction – dermatitis. The study was conducted at the Department of General and Private Surgery of the SPbGUVM, based on the clinic of small pets. For the study, 3 random groups of animals, 10 dogs each, were selected. In the first group – 10 animals with common dermatitis, in the second –10 dogs with follicular cyst of the interdigital skin of localized course, and in the third – 10 with follicular cyst of the interdigital skin in combination with common dermatitis. Whole blood was obtained from all animals, and blood plasma was used as a sample for testing using species-specific rapid tests for qualitative determination of the concentration of Ig-E and CRP in the blood of dogs. The results of the study were entered into the table, and then these indicators were calculated according to the "criterion X2", using the statistics program – "Biostat". The study revealed that in dogs with follicular cyst of the interdigital skin, in combination with a pronounced dermatological reaction, there is a systemic inflammatory response of the body, and in animals with a localized course of pathology, with the presence of only hair follicle cysts, the intensity of the systemic inflammatory response remains at a low.