Abstract
This study aimed to assess the systemic effect of LLLT on thyroid gland functioning and consequently on calcium regulation through Triiodothyronine (T3) and Thyroxine (T4) measurements in rabbits’ serum. A total of thirty two New Zealand male rabbits were randomly distributed in four groups with eight animals each: control group C (nonirradiated animals), group EI (5 J/cm2 per session), group EII (10 J/cm2 per session) and group EIII (20 J/cm2 per session). All animals underwent lower left incisor extraction followed by immediate insertion of an osseintegrated implant, providing an equality of initial clinical condition between the groups. The experimental groups were irradiated with aluminium gallium arsenide diode laser (GaAlAs, λ = 830 nm, 50 mW, CW), during 13 days at each 48 hours, totalizing 7 sessions. Laboratorial T3 and T4 measurements were done in four distinct moments (before surgical procedure, immediately after surgical procedure, after the first LLLT session and after the last LLLT session) in all animals. The results obtained showed statistically significant differences in Triiodothyronine values between the groups throughout the experiment. It was concluded that the LLLT, in the protocol of irradiation used in this study, promoted a significantly alteration on rabbits’ serum hormonal levels.
Highlights
The devices of laser radiation are widely used by health care professionals, mostly for therapeutic uses and complementary diagnosis
This study attempted to assess the systemic effect of level laser therapy (LLLT) in thyroid gland function through measurement of serum levels of Triiodothyronine (T3) and Thyroxine (T4) in blood samples serially collected
Evaluating separately the values found for each one of the studied laboratory tests, it’s observed that Triiodothyronine (T3) countings presented significant variations when taking into consideration the low level laser therapy (LLLT), but throughout the experiment (Table 3)
Summary
The devices of laser radiation are widely used by health care professionals, mostly for therapeutic uses and complementary diagnosis. The clinical use of LLLT (low level laser therapy) is grounded on its capacity of promoting stimulating effects, at cellular level, on the biochemical and molecular processes that occur during the intrinsic mechanisms of tissue repair. According to some authors [15], the irradiation dose is the most important parameter in laser therapy and, even so, there is still no definitive protocol for its use in different clinical situations, which makes these parameters a matter of literature discussion [16,17,18,19,20,21,22,23,24,25] (Table 1)
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