Assessment of lipid profile in post menopausal women

Abstract

Background: Younger age at menopause is associated with greater risk for coronary heart disease (CHD) and all-cause mortality. The present study was conducted to assess lipid profile in post menopausal women. Materials & Methods: 80 women in age ranged 20-60 years were divided into 2 groups. Group I comprised of premenopausal women (20- 40 years) and group II post menopausal women (40-60 years). 5 ml of venous blood was withdrawn from anticubital vein with full aseptic precautions. Clear unhaemolysed serum was obtained by centrifugation. Estimation of serum lipids such as total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C), very low density lipoprotein (VLDL) was done. Results: The mean TC (mg/dl) in group I was 178.2 and in group II was 246.4, TG was 126.2 and 138.4, HDL- C was 62.4 and 42.8, LDL- C was 132.8 and 232.6 and VLDL was 26.2 and 28.0 in group I and II respectively. The difference was significant (P< 0.05). Conclusion: Higher level of lipid profile in post menopausal women increases the risk of cardiovascular diseases.