Assessment of left ventricular global systolic strain in patients with hypertrophic cardiomyopathy after modified Morrow surgery by two-dimensional speckle tracking imaging

Abstract

Objective To evaluate left ventriclular systolic function in patients with obstructive hypertrophic cardiomyopathy (HOCM) after modified Morrow surgery using two-dimensional speckle tracking imaging (2D-STI). Methods Twenty three HOCM patients were recruited in this study. Echocardiographic data from HOCM patients during pre-operation, 1-month and 3-month post-operation were analyzed by Qlab software to compare the variation in systolic function indicators 1-month and 3-month post-operation including global and 16 segmental longitudinal strain, circumferential strain and conventional echocardiographic parameters of left ventricle. Results Compared with preoperative data of HOCM patients, postoperative LVOT diameter and pressure gradient, left atrial diameter and volume index were significantly decreased(P<0.05), but there was no significant difference in left ventricular ejection fraction(P<0.05). Compared with the preoperative case, global and segmental longitudinal strain showed significant reduction after 1 week and gradually recovered after 3 months, without significant variation. The longitudinal strain of the anteroseptum reduced significantly and the longitudinal strain of the free wall increased after 3 months, however, the circumferential strain reduced significantly. The circumferential strain of basal and middle segment after 3 months had improved significantly than those of postoperative 1 week. The circumferential strain of surgical site is no obvious change and the strain of free wall was improved after 3 months. Conclusions 2D-STI can effectively evaluate global and regional systolic function of left ventricle for HOCM patients after modified Morrow surgery. Key words: Echocardiography; Cardiomyopathy, hypertrophic; Ventricular function, left; Two-dimensional speckle tracking imaging