Assessment of Laboratory Parameters in Acute Stroke Patients Underwent Decompression Surgery

Abstract

Objective: Decompression surgery is applied as a life-saving treatment in patients with malignant cerebral edema. We aimed to evaluate the effect of laboratory parameters such as C-reactive protein and albumin ratio in predicting decompression surgery at an early stage in acute stroke patients. Material and Method: Demographic characteristics, CRP and albumin values, decompression surgery time, NIHSS and mRS scores of 53 stroke patients who underwent decompression surgery were listed. The patients were grouped according to the time of decompression surgery as 0-24th hours, 24th-48th hours, 48th-72th hour and after 72th hours and the laboratory parameters of each group were evaluated. Results: The mean age of 31 male and 22 female patients was 61±14 (34-91) years. There was no significant difference between the groups in terms of gender, NIHSS, and mRS scores. A statistically significant difference was detected between the first and second groups (p=0.024) when comparing the CRP and albumin ratios. Conclusion: Markers of inflammation, serum CRP, and albumin ratios were evaluated to determine their usefulness in suggesting the timing of surgical treatment. It was observed that a high CRP and albumin ratio at the time of admission could serve as a predictive factor for surgery within the first 24 hours. Our findings suggest that patients with a high CRP albumin ratio may require surgical treatment within the first 24 hours.