Abstract
Vector-borne diseases pose serious threat to life and socio-economic status of an individual and application of insecticides has always been a prime strategy to control the vectors. However, with frequent use of insecticides the vectors develop resistance towards the same. It is therefore necessary to evaluate the resistance status of vectors against such chemicals for proper management of vector-borne diseases. As such, field populations of Culex quinquefasciatus a vector of lymphatic filariasis were collected 3 districts of West Bengal and mortality percentage was studied against 6 insecticides. Quantitative assay of major detoxifying enzymes was also studied to unveil their association with insecticide resistance and the presence of mutation in the voltage-gated sodium channel (L1014F) was also evaluated. This study showed multiple resistance to all of the insecticides used i.e., deltamethrin, lambdacyhalothrin, permethrin, DDT, propoxur and malathion). The presence of high frequency of L1014F mutant allele and enhanced enzyme activity may indicate their involvement in the development of insecticide resistance.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
