Assessment of Incidence of Metachronous Neoplasms after Surgical Resection of Colorectal Cancer

Abstract

Abstract Background Cancer colon is the second most common cause of cancer in women and the third most common in men. Globally incidences vary 10-fold with highest rates in Australia, New Zealand, Europe and the US and lowest rates in Africa and South-Central Asia. However, in Egypt, CRC represent 4.2% of all cancers in male and 3.8% in females. Aim of the Work The aim of our study was to assess the incidence of Metachronous neoplasms after curative surgical resection of colorectal cancer and assess different risk factors for metachronous Cancer colon occurrence. Patients and Methods We enrolled 100 patients in this retrospective cohort study to predict incidence and risk factors of metachronous colorectal cancer (CRC) after 6 months of curative surgical resection of colorectal cancer. Results After 6 months of post-operative follow up, 90% of cases had no recurrence of CRC, 5% had polyps and did polypectomy, 5% had mass lesion. So patients were divided into two groups, Group (1) included patients with no recurrent CRC. Group (2) included patients with recurrent CRC. The incidence of metachronous CRC was 5% for mass and 5% for polyps in patients who underwent curative surgical resection of colorectal cancer. In both Univariate and multivariate Logistic regression analysis for the parameters affecting recurrent mass, DM was the only significant risk factor associated with the incidence of metachronous CRC with P values (0.043, 0.049) respectively. Conclusion The incidence of metachronous CRC in this study was 5% for mass and 5% for polyps in patients who underwent curative surgical resection of colorectal cancer. DM is a significant risk factor of metachronous CRC.