Abstract
The present study aims to evaluate the adverse effects of contaminated urban river water on fish. Hepatic antioxidant parameters, including the activities of catalase, superoxide dismutase, glutathione peroxidase and glutathione S-transferase, as well as glutathione content, were significantly inhibited in zebrafish upon 14-d exposure to urban river water sampled from Shanghai, China, which was determined to be potentially contaminated by environmental estrogens (EEs) using the yeast estrogen screen bioassay. However, using estradiol as an estrogen standard for exposure, our results did not show a direct correlation between EE contamination and impairment of the antioxidant defense system of fish.
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