Abstract
BackgroundMany studies revealed toxic effects of pesticides on pesticide handlers but very fewer studies have been reported among grape garden pesticide sprayers in India. The purpose of this study was to evaluate the effect of pesticides among grape garden sprayers.Methods27 pesticide sprayers in study group and 27 non sprayers in control group were recruited. Blood samples were analyzed for hematological profile, biochemical parameters and urine samples for oxidative stress, buccal mucosal cells for genotoxicity. For statistical analysis student’s t-test and Mann Whitney U test were used.ResultsWhite blood cell (WBC) count was significantly decreased; uric acid and Malondialdehyde (MDA) level was significantly increased among study group. In present study the Micronucleus (MN) assay for buccal mucosal cell showed significant number of micronucleated cells in study group.ConclusionThese results suggest that pesticide sprayers in grape garden are under risk which need to be monitored continuously in large population and further study is warranted to correlate the pesticide exposure by assessing acetylcholinesterase activity, pesticide residue analysis and their personal habits.
Highlights
Many studies revealed toxic effects of pesticides on pesticide handlers but very fewer studies have been reported among grape garden pesticide sprayers in India
Our result showed no significant differences between Red Blood Cell (RBC), platelet count and Hb values in study group and control groups except in White blood cell (WBC) count which was significantly decreased in study group
Present study shows that study group is more likely affected as compare to control group in association with decrease in WBC count and increase in level of uric acid
Summary
Many studies revealed toxic effects of pesticides on pesticide handlers but very fewer studies have been reported among grape garden pesticide sprayers in India. The purpose of this study was to evaluate the effect of pesticides among grape garden sprayers. India is among the first ten countries in the world in the production of grape. This crop occupies fifth position amongst fruit crops in India with a production of 1.21 million tonnes (around 2% of world’s production of 57.40 million tonnes) from an area of 0.05 million hectare in 2001–02 [2]. Short term poisoning effects like nausea, vomiting, headache, chest pain, eye, skin and throat irritation etc.
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