Assessment of health status in fiber glass workers: Role of chromium with biological antioxidants.

Abstract

Objectives: The aim of study is to find out the role of chromium with biological antioxidant and how these can relate with the health of fiber glass workers. Study Design: Cross Sectional Study. Setting: Fiber glass industry Lahore. Period: July 2018 to Feb 2019. Material & Methods: Study was included the fifty workers of fiber glass industry with 4-5 years experience or time of exposure. A questionnaire was filled by each participant. Twenty individuals were taken as controls. Their blood sample was drawn to estimate the level of chromium and of biological antioxidants that include serum Catalase, Superoxide Dismutase, Glutathione and Malondialdehye. Results: Mean age of workers was 35 year with BMI 23.80 kg/m2. Their work duration in Fiber glass factory was 6-7 years. Levels of serum chromium and the biological antioxident was significantly high (P<0.001) in fiber glass workers as compared to the levels of these parameters of control. A positive weak correlation was observed between serum chromium and antioxidants MDA, SOD and catalase. On the other hand a moderate inverse correlation was observed between serum chromium and antioxidant GSH. Conclusion: It is concluded that high level of chromium in workers of fiber glass factory is responsible for increased levels of antioxidants in their body, which in long run may develop the diseases especially of respiratory tract.