Abstract
Objective:We investigated the health-related quality of life (HRQL) in survivors of pediatric acute lymphoblastic leukemia (ALL) and evaluated the perceptions of the children, their siblings, and their parents.Materials and Methods:Seventy ALL survivors, who were between 7 and 17 years of age and had completed therapy ≥2 years, were included. The control group consisted of their healthy siblings. HRQL was assessed by the age-specific KINDLR questionnaire.Results:No significant differences could be found among HRQL scores of ALL survivors with respect to variables such as sex, risk group, and having chronic illness. HRQL scores for physical well-being, emotional well-being, family, and social functioning of the patient and sibling self-reports and parent proxy reports were lower than the expected values for healthy and chronically ill children.Conclusion:These results demonstrate that both ALL survivors and their families need help via psychological counseling programs to improve their HRQL even after completion of therapy.
Highlights
Acute lymphoblastic leukemia (ALL) comprises 26%-28% of all childhood malignancies [1,2]
No significant differences could be found among health-related quality of life (HRQL) scores of ALL survivors with respect to variables such as sex, risk group, and having chronic illness
HRQL scores for physical well-being, emotional well-being, family, and social functioning of the patient and sibling self-reports and parent proxy reports were lower than the expected values for healthy and chronically ill children
Summary
Acute lymphoblastic leukemia (ALL) comprises 26%-28% of all childhood malignancies [1,2]. The outcome of ALL has improved and survival periods have become longer [3,4]. Five-year overall survival was 79.9% at our centers between 1995 and 2009 [5]. Investigations of survivors have documented that their quality of life is negatively affected, with difficulties in social and intellectual functioning [6,7,8,9,10]. The aim of this study was to investigate health-related quality of life (HRQL) in survivors of pediatric ALL and to evaluate the perceptions of the children, their siblings, and their parents. Received/Geliş tarihi: October 10, 2018 Accepted/Kabul tarihi: November 06, 2018
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