Abstract

Smoking is most common in Libya state, where about two thirds of all adults Smoke tobacco; cigarette smoking is by far the most common. SHby far the most common. Smoking is the primary cause of chronic obstructive lung disease, chronic bronchitis and piratory symptoms. Many studies have shown a nificant change of FVC, FEVI & FEV1/FVC% in adult smokers. Obje kers. Objective: To assess the change of FVC, FE & FEV1/FVC% in adult male smokers. Method: This cross-sectiond: This cross-sectional comparative study was carried out the Department of Physiology, Medical faculty, Benghazi and Chelty, Benghazi and Chest clinic Benghazi Medical center (BMC), 1 February 2012 orary, 2017 to 30th August, 2017. For this purpose. 90 adult male subjects ranging from 18 to 52 years 4. The subjects were divided into two groups - A and B. Group A consisted of 30 apparently healthy adult male non-smokers. Group B consisted of 60 apparently healthy adult ently healthy adult male smokers. The experimento group was again subdivided into group B1 consisting of 20 smokers consuming consuming 2-10 cigarettes/day for more than 5 years, group B2 consisting of 20 smokers cons, group B2 consisting of 20 smokers consuming 11-20 cigarettes/ day for more than 5 years an sroup B3 consisting of 20 smokers consuming >20 cigarettes/day for more the dove for more than 5 years. Analysis of data wae one with the help of com With the help of computers by SPSS 16,0 programmers and significant tests were done by unpaired student's "t" test. Results: There were no statistically significant an there were no statistically significant differences of PVC, FEV1 in group A vs. Rroun R group B2 vs. group B3. The mean FVC, FEV1 were significantly lower (<0.05) in group A vs. group B, group A vs. group B2, group A vs. group B3, group B1 vs. group B2 & group Bl vs. group B3. There were no statistical significant differences of
 can't differences of FEV1/ FVC% among different groups. Conclusion: From the statistical analysis of the results obtained in the present study and their comparison with those of published reports, it may be concluded that smoking causes significant change of PVC FEV1 among the smokers and no significant chanen of FEV1/FVC% who consumed more than 10 cigarettes per day for more than five years.

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