Assessment of functional group in herbal formulation sathakuppai chooranam through fourier transform infrared spectroscopy

Abstract

Background: The Sathakuppai chooranam is a single herbal medicine used in the treatment of Kumbavatham (Periarthritis). Objective: This study is aimed to evaluating the morphology and elemental charecterization of the Sathakuppai chooranam. Materials and methods: The ingredients were collected and purified and the drug was prepared as per Siddha literature Siddha Vaithiya Pathartha Guna vilakkam. It is subjected into characterisation through FT-IR analysis. Results: The FT-IR characterization showed the presence of functional groups like O-H stretching (carboxylic acid, alcohol molecule), N-H stretching (amine salt),C-H stretching (alkene), N-H stretching (amine salt), C-H stretching (alkene),C=C stretching (conjugate alkene, cyclic alkene,alpha beta unsaturated ketone), N=H bending (amine),O-H bending (carboxylic acid, alcohol),C-O stretching (alkyl aryl ether, primary alcohol), C-N stretching (amine), S=O stretching (sulfoxide), C=C bending (alkene), C-Br stretching (halo compund)which ensures the therapeutic effect of drug. Conclusion: The instrumental analysis FT-IR study for Sathakuppai chooranam shows the presence of functional groups through the stretch and bends which is responsible for its functional activity. The functional groups present in Sathakuppai Chooranam have analgesic, anti-inflammatory activities. This will ensure the efficacy and therapeutic effect of Sathakuppai Chooranam. This study forms the base for the pharmaceutical analysis of the Sathakuppai Chooranam.