Abstract
Quantitative computed tomography (QCT) provides three-dimensional bone mineral density (BMD) of trabecular and cortical components separately, as well as macroscopic bone configuration. High resolution CT (HRCT) measures bone geometry more precisely than conventional CT, which enables to assess the effects of anti-osteoporotic agents. HRCT is also able to analyze in vivo trabecular microstructure. CT has an advantage to demonstrate the trabecular microstructure in axial skeleton such as vertebra or hip, which can be expected to contribute to evaluate the effects of anti-osteoporotic agents.
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