Abstract

ObjectiveThis study was conducted to assess magnitude and pattern of drug related problems among patients with type 2 diabetes mellitus (T2DM) and hypertension.ResultsThis study identified 364 drug related problems (DRPs) across the three categories of drug related problems, giving an average of 1.8 DRPs per patient. The effect of drug treatment being not optimal 179 (49.2%), untreated indication and symptoms 77 (21.1%), unnecessary drug-treatment 39 (10.7%) and adverse drug reactions 69 (19%) were the most frequent categories of DRPs identified. In general, high prevalence of drug-related problems was identified among patients with T2DM hypertension. The effect of drug treatment being not optimal, untreated indication and symptoms, unnecessary drug-treatment and adverse drug reactions were the most frequent categories of drug related problems identified. Therefore, the clinicians should work to improve patient care through prevention and resolving drug related problems since it can affect the quality of the care significantly.

Highlights

  • Diabetes mellitus is a group of metabolic disorders caused either by the inability to produce insulin or by the body not being able to use insulin effectively or both [1]

  • Drug related problems in type 2 diabetic with hypertension patients In this study, 364 drug related problem (DRP) were identified which is about 1.8 DRPs per patient

  • This finding is lower than study conducted among Jordan [19] ambulatory patients where 11.2 DRPs per patient were reported but higher than study conducted in Nigeria [20] and southern Ethiopia [21]

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Summary

Introduction

Diabetes mellitus is a group of metabolic disorders caused either by the inability to produce insulin or by the body not being able to use insulin effectively or both [1]. 415 million adults are estimated to have diabetes currently and there are 318 million adults with impaired glucose tolerance which puts them at high risk of developing the disease in the future. Developing countries is suffering from increasing burden of diabetes mellitus [1, 2]. In 2015, it was estimated that 9.5–29.3 million peoples live with diabetes in the Africa Region [3]. American diabetic association classification categorizes diabetes into four categories; type 1, type 2, gestational and other diabetes [4]. T2DM accounts for 90–95% of the incidence of diabetes and is associated with a strong

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