Abstract
Left ventricular (LV) diastolic abnormalities (LVDA) represent the earliest manifestation of most myocardial diseases. Especially, LVDA precede in arterial hypertension (HTN) the development of LV hypertrophy [1] as well as LV systolic dysfunction.
Highlights
Assessment of Diastolic Behavior of Patients with Hypertension vs. other Myocardial Diseases Using an External Pressure Transducer and Short Handgrip Exercise
It has been excessively shown that the use of both pressure sensors and volumetric techniques represents the ideal method for assessing diastolic dysfunction, Left ventricular (LV) pressure (LVP) derived diastolic measures are widely accepted and almost exclusively used as standard
The widely applied Doppler echocardiographic diastolic indexes are expected to represent as volumetric variables only dubious estimates of diastolic LVP changes [3] showing profound limitations for assessing noninvasively LV diastolic dysfunction
Summary
It has been excessively shown that the use of both pressure sensors and volumetric techniques represents the ideal method for assessing diastolic dysfunction, LV pressure (LVP) derived diastolic measures are widely accepted and almost exclusively used as standard. The widely applied Doppler echocardiographic diastolic indexes are expected to represent as volumetric variables only dubious estimates of diastolic LVP changes [3] showing profound limitations for assessing noninvasively LV diastolic dysfunction. Pressocardiogram is a very old noninvasive technique that has been used widely in noninvasive laboratories in and out of hospitals by applying transthoracically an optimal pressure sensor over the maximal LV impulse. Several pressocardiographic temporal and relative amplitude indexes have been found to correlate significantly with corresponding widely accepted diastolic measures derived from high-fidelity LVP curve recordings [5,6,7]. The most frequently used indexes are the total relaxation time from the begin of 2nd heart sound in phonocardiogram to the lowest point of Pressocardiogram [5] and the relative A wave to total pressocardiographic height [6,7]
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