Assessment of Dental Implant Stability Using Two Platelet-Rich Fibrin Proto-cols (A Comparative Clinical Study)

Rayan Hamed,Rahma Kamal

doi:10.33899/rden.2021.128684.1059

Abstract

Aims: The current study aimed to compare implant stability of dental implants covered with one of two - platelet rich fibrin preparation protocols namely Standard-Platelet Rich Fibrin and Advanced-Platelet Rich Fibrin) using radiofrequency assessment. Materials and methods: A total of ten male patients with an age range of 28-51 years participated in this split-mouth clinical study. The patients were divided into two groups based on the platelet rich fibrin (PRF) protocol to be used with dental implant insertion into positive control (S-PRF) and study group (A-PRF). Each patient represented the two groups in which he received 2 dental implants; ten implants for each group (a total of 20 dental implants) of standard length and diameter in the posterior mandibular extraction sites of ipsilateral or contralateral side. In the positive control group, the standard PRF protocol was to be used to prepare the PRF clot. In the study group, the advanced PRF protocol was to be used to prepare the PRF clot. Both PRF membranes were to be instilled inside the osteotomy bed during dental fixture installation. Following the installation of dental implants; radiofrequency assessment using Osstell Mentor Device immediately after insertion, four, eight; twelve weeks post-operative as secondary outcomes were conducted. Results: When comparing ISQ means of dental implants between both group protocols, the Friedman test values of ISQ means showed no statistically significant difference between them at the immediate day of surgery, four weeks, eight weeks and twelve weeks post-surgery yet showed increased levels of ISQ at end of the trial. Conclusions: Both S-PRF and A-PRF, similarly enhanced and maintained dental implant stability hence maintain osseointegration (synergistic effect) throughout the period of study and as disclosed by ISQ values. The use of PRF in its current forms seems to be an accepted minimally invasive approach with good clinical results.

Highlights

Achieving a short and uneventful implant osseointegration period could make immediate or early loading of a dental implant more reasonable and predictable
The patients were divided into two groups based on the platelet rich fibrin (PRF) protocol to be used with dental implant insertion into; positive control (S-Platelet-rich fibrin (PRF)) and study group (A-PRF).Each patient represented the two groups in which he was to receive 2 dental implants / Superline / Implantium / Dentium Corporation, South Korea; ten implants for each group of standard length and diameter
Bone quality around the dental implants was judged according to Lekholm and Zarb classification and as follows; 6 implants were placed in type 1 bone density, 12 implants in type 2 bone density and two in type 3 bone density

Summary

Introduction

Achieving a short and uneventful implant osseointegration period could make immediate or early loading of a dental implant more reasonable and predictable. Platelet-rich fibrin (PRF) is frequently used to accelerate wound healing. The activated platelets in the PRF clot secret growth factors, which in turn enhance cellular proliferation, collagen synthesis, and osteoid production [1]. Platelet concentrates for topical use have evolved as surgical adjuncts or suspensions in the field of regenerative medicine. They are autologous blood extracts transplanted to an injured site to improve local healing. Improving healing is a constant issue in all surgical disciplines [2]

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Conclusion