Abstract
OBJECTIVE: Embryo morphology and cleavage rate are widely used for embryo viability assessment in the IVF laboratory. Recently, metabolomic profiling of embryo culture media was reported to correlate with the reproductive potential of embryos, allowing the generation a numerical “Viability Score”. In this study, we used Receiver Operator Curve (ROC) analysis to compare (i) morphologic grading (ii) the Viability Score and (iii) a combination of morphology and the Viability Score as predictors of implantation potential of Day 5 embryos.
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