Abstract
Background: There is an increase in elderly population and memory-related disorders. Curcuma longa linn. can induce cognitive improvement due to its antioxidant effects. This study evaluated the effect of chronic administration of C. longa linn. on learning and memory in rats. Methods: Twenty four female Albino Wistar rats were randomized into control, standard, and test groups. The control group received 0.5% methyl cellulose; the standard group received piracetam and test group received C. longa orally for 24 days. Water maze and step-through passive avoidance test were used to evaluate the effect of C. longa linn. on learning and memory. Water maze training was done from day 23 to day 26. Assessment of spatial memory was done on day 27 and retention memory on day 29. Results: The mean escape latency (EL) in control, standard, and test group was 42.48, 30.45, and 30.88 sec on day 23 which decreased to 11.08, 11.36, and 9.66 sec on day 26, respectively. The EL in all the three groups decreased from day 23 to day 26 (p
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Basic and Clinical Pharmacology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
