Abstract
Purpose The aim of this study was to evaluate the effect of soft contact lens (SCL) use on corneal thickness measured by anterior segment optical coherence tomography (AS-OCT). Patients and methods The epithelial and overall thicknesses of both the central cornea and the nasal and temporal cornea of SCL wearers (25 patients) were obtained by AS-OCT and compared with those of refraction‐matched controls (25 individuals) and patients with emmetropia (25 patients). Results The mean corneal epithelial thickness in SCL-wearing, spectacle-wearing, and emmetropic groups was 48.13±2.39, 51.92±2.81, and 53.13±2.11 μm, respectively. The corneal epithelium of members of the SCL group was significantly thinner than both the spectacle-wearing and emmetropic groups (P=0.000 and 0.006, respectively). The central corneal thickness in SCL-wearing, spectacle-wearing, and emmetropic groups was 517.67±21.95, 562.53±20.58, and 547.83±26.71 μm, respectively. The corneal thickness of the SCL group was significantly thinner than both the spectacle-wearing and emmetropic groups (P=0.0395 and 0.0255, respectively). Conclusion Contact lens wear is related to thinning of both corneal thickness and epithelium. AS-OCT is a noninvasive and clinically applicable technique used to assess assessing the involvement of the cornea in contact lens wearers.
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