Assessment of cognitive impairment

Abstract

Objective: assessment of the usefulness of quantitative electroencephalographic analysis as an indicator of cognitive impairment, we examined the correlation between Mini-Mental State Examination (MMSE) scores & Montreal Cognitive Assessment(MoCA) & intelligence quotation (IQ) on one hand and quantitative electroencephalographic (QEEG) power values in elderly patients and healthy controls on the other hand and conducting Stepwise multiple regression analysis to calculate the predicted MMSE score from the QEEG power values. Methods: We evaluated brain function using QEEG in 29 elderly patients with memory complaints and 29 healthy volunteer and compared their results with their MMSE &MoCA& IQ scores. Results: in our study we reached to a significant negative correlation between MMSE &MoCA& IQ scores. and QEEG relative theta Ɵ and delta δ power values and significant positive correlation was found between MMSE &MoCA& IQ scores. and QEEG relative alpha α and beta β power values. And the regression model created using relative QEEG and gender for predicting MMSE scores had an adjusted R2 of 0.69. Conclusions: These results suggest that QEEG analysis can be a helpful tool of cognitive testing in patients with abnormalities in memory