Abstract

Retinal vasculitis (RV) is an intraocular inflammation that predominantly affects retinal vessels of either arterial and/or venous system and can be associated with numerous infectious and non-infectious disorders though many cases remain idiopathic. Inflammation of the retinal vasculature may occur as an isolated intraocular disorder or in association with various systemic diseases. The list of associated systemic diseases is extensive and includes various systemic disorders such as Behcet's disease, multiple sclerosis, sarcoidosis, systemic autoimmune disease as well as infectious diseases including herpetic viral infection, toxoplasmosis, and syphilis. Hence based on above findings the present study was planned for Assessment of Clinical Profile of Retinal Vasculitis in IGIMS, Patna, Bihar.
 The present study was planned in Regional Institute of Ophthalmology, IGIMS, Patna, Bihar, India. The 50 cases of the retinal vasculitis were enrolled and evaluated in the present study. Patients were diagnosed with RV if the intraocular inflammation was located mainly in the retinal vasculature. Ocular findings included perivascular sheathing and inflammation located along the vessels associated with cotton wool spots, retinal exudates, retinal hemorrhages, ischemia or neovascularization.
 The data generated from the present study concludes that the diagnosed cases of the primary retinal vasculitis shows no systemic disease association or infectious etiology could be ascertained after detailed history, clinical examination and tailored laboratory work-up. The finding that retinal vasculitis cases were primary in nature may lead to an approach where laboratory investigations are advised sparingly, based mainly on previous systemic history and clinical judgment.
 Keywords: Clinical Profile, Retinal Vasculitis, IGIMS, Patna, Bihar, etc.

Highlights

  • The present study was planned in Regional Institute of Ophthalmology, IGIMS, Patna, Bihar, India

  • The data generated from the present study concludes that the diagnosed cases of the primary retinal vasculitis shows no systemic disease association or infectious etiology could be ascertained after detailed history, clinical examination and tailored laboratory work-up

  • The finding that retinal vasculitis cases were primary in nature may lead to an approach where laboratory investigations are advised sparingly, based mainly on previous systemic history and clinical judgment

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Summary

Introduction

Retinal vasculitis can be an isolated condition or a complication of local or systemic inflammatory disorders characterized by inflammation of the retinal vessels. It is a sight-threatening condition associated with various infective, auto-immune, inflammatory or neoplastic perivascular sheathing or cuffing, vascular leakage and/or occlusion.[4][5] It may be associated with signs of retinal ischemia, including cotton-wool spots and intra-retinal hemorrhage. Retinal vasculitis was thought to be an extension of the systemic disease.[2] there are major differences between the two, because of the unique microstructure of the retinal vessels. Unlike systemic vasculitis, retinal vasculitis is not associated with vascular necrosis.[3]

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