ASSESSMENT OF CLINICAL OUTCOME AND THEIR RISK FACTORS IN PATIENTS WITH STROKE

Abstract

Globally, stroke is the second leading cause of mortality and disability. In india, 619000 in 9.4 million deaths were due to stroke. There is paucity of information regarding the factors affecting clinical outcome in stroke patients. This study aims to assess the risk factors associated with clinical outcomes in patients with stroke. A prospective observational study was conducted in neurology unit of a tertiary care teaching hospital with a total of 80 patients over a period of six months. During the study period, the subjects were followed till discharge to assesss the prescribing pattern and clinical outcomes. The clinical outcomes were assessed using modied ranking scale (mRS), Glasgow coma scale (GCS) and muscle power grading scale (MRC). Among the study subjects, 48(60%) were male, 40(50%) were aged 60 years and above. Patients received an average of 10.38 drugs during hospital stay, in which 77 (96.25) were prescribed with atorvastatin and 35(43.75%) with heparin. A combination of aspirin-clopidogrel was received by 70(87.5%). Total of 49(61.25%) patients had a good clinical outcome at the time of discharge. Mortality rate during hospitalization was foud to be 5%. The study concludes that factors such as age of 60 years and above, family history, polypharmacy, co-morbidities and length of hospital stay contribute to a negative clinical outcome in stroke patients.