Assessment of changes in biochemical parameters and their role as markers of pathological processes

Abstract

The data of laboratory tests can often provide up to 70% of information about the disease, and the test results can help the doctor not only in the correct diagnosis and competent prescription of treatment, but also should be aimed at conducting a subsequent assessment of its effectiveness. At the present stage, laboratory tests are represented by a wide range of clinical, immunological, biochemical, microbiological, histological and molecular genetic studies. Evaluation of some parameters (for example, a clinical blood test and a general urinalysis) is carried out practically at each patient's request for medical help, while others are evaluated only if there are indications. For example, if a patient complains of severe dysuric disorders, determining the level of amylase in this case will be uninformative, but urinalysis according to Nechiporenko will contribute to the correct diagnosis. A doctor of a clinical specialty, on the one hand, must clearly understand which tests can help in making a diagnosis and will carry the maximum information content, and, on the other hand, try to avoid unnecessary prescription of tests that have low evidence in a particular clinical situation. One of the most frequently prescribed tests is the conduct of biochemical studies, therefore, in today's article we will try to figure out how biochemical parameters change in various pathological processes, and what information they can bring.