Assessment of cardiovascular risk in patients with chronic periodontitis

Abstract

Abstract Introduction To effective prevention of cardiovascular morbidity and mortality in populations with an unfavorable cardiovascular profile, it is important to analyze the occurrence and severity of traditional risk factors and the calculated risks of cardiovascular events. Aim Estimation of cardiovascular risk in patients with chronic periodontitis (CP) different severity. Methods We examined 2400 person (65.6% male, aged from 40 to 64 years), of these 466 had health periodontium (HP), 1934 had CP different severity. Considered exclusion criteria were known diabetes and cardiovascular diseases. The 10-year risk of a cardiovascular event was calculated using SCORE (Systematic Coronary Risk Evaluation) and Reynolds Risk Score (RRS). Results There were no differences between the groups with HP and mild CP in the incidence of calculated 10-year risk of a cardiovascular event. Severity of periodontitis was associated with a higher cardiovascular risk on the SCORE. High risk on the SCORE in the group with HP was found in 10.3%, and in patients with moderate and severe CP-in 34.1%, 48.5% respectively. Using the RRS among 538 patients with moderate risk on the SCORE was showed the results: 48 (8.9%) patients were classified as low risk, 258 (48%) - the moderately low risk category (5% to 10%), 192 (35.7%) patients -a moderately high risk (10% to 20%) and 40 (7.4%) - high risk (≥20%). There was an association between SCORE index with the number of missing teeth (Spearman's R=0.591) and the loss of periodontal bone according to panoramic x-ray (R = 0.46). RRS index correlated with the severity of periodontal inflammation: the periodontal index (R=0.43), and the depth of periodontal pockets (R=0.38). Conclusion The relationship between the results of severe CP as missing teeth, loss of periodontal bone and the risk of fatal cardiovascular events is important for clinical use and can be an additional cardiovascular risk marker for patients with CP. Funding Acknowledgement Type of funding source: None