Abstract
Hepatitis C virus (HCV) is one of the leading causes of chronic liver disease worldwide. Itposes a serious health risk. Liver cirrhosis of is also linked to a variety of cardiovascular abnormalities.Nowadays, direct-acting antivirals (DAAs) for hepatitis C have the potential to reducethis disease burden, but their potential long-term cardiac effects are unknown. The aim of thiswork was to see how direct-acting antivirals affect the cardiac functions of naive Egyptianswith chronic hepatitis C.The 90 treatment-naive adult patients with chronic hepatitis C were divided into two groups(cirrhotic and non-cirrhotic). Only two patients within the non-cirrhotic group and a patientamong cirrhotic patients showed nonspecific ST segment changes which remained unchangedafter treatments. Two non-cirrhotic patients and four cirrhotic patients showed T wave inversion,which remained static post treatment, but without significant difference in corrected QTinterval before & after treatment between groups.
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