Abstract
In this study, we aimed to evaluate adherence to active vitamin D and calcium replacement in patients with post-surgical hypoparathyroidism. To elucidate the medication adherence, we performed a questionnaire survey using the six-item "Medication adherence questionnaire"(MAQ). The first, second, and sixth questions reflect the motivation status of the patients whereas the third, fourth, and fifth questions reflect the knowledge about the medication that is received. The responses are scored and patients are classified regarding their motivation to and knowledge about the particular drug. Totally, 64 patients (male: 12/female: 52; mean age 48.6±11.6 years) who had post-operative hypoparathyroidism were included in our study. Median disease durance was 60 months (min-max: 12-295 months). We found that motivation score of calcium usage was significantly lower compared to vitamin D usage (p<0.001). The calcium motivation score was reversely correlated with disease duration (r= -0.256 and p=0.046). The most common worry about calcium usage was nephrotoxicity, and the most common worries about calcitriol treatment were kidney damage and polyuria. One-third of the patients were taking oral calcium and calcitriol less than the recommended dose. One-third of patients lack motivation to use calcium whereas half of the patients experiences anxiety about drug-related side effects. This is a preliminary study showing that vital calcium and active vitamin D intake may be interrupted due to side effect anxiety.
Highlights
In this study, we aimed to evaluate adherence to avtive vitamin D and calcium replacement in patients with post surgical hypoparathyroidism
Summary: In this study, we found that patients with hypoparathyroidism had a problem with calcium medication compliance, and this problem increased with the duration of the disease
We found that motivation score of calcium usage was significantly lower compared to vitamin D usage (p
Summary
We aimed to evaluate adherence to avtive vitamin D and calcium replacement in patients with post surgical hypoparathyroidism. Hypoparathyroidism (HypoPT) is defined as dysfunctional production and/or secretion of parathormone (PTH) by the parathyroid glands. It is characterized with hypocalcemia and hyperphosphatemia. While treating the patients with hypoPT there are 6 applied principles used for monitoring. Those are as follows;1) serum Ca should be slightly below normal 2) there should be no sign or symptom of hypocalcemia 3) Serum CalciumPhosphorus (Ca-P) product to below 55 mg2/dL2 (4.4 mmol/L); 4) to avoid hypercalciuria; 5) to avoid hypercalcemia; and 6) to avoid renal (nephrocalcinosis/nephrolithiasis) and other extra skeletal calcifications [4]. For the treatment of hypoPT, calcium and activated Vitamin D replacement are used
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
