Abstract
ABSTRACT Cypermethrin (CYP) is a synthetic pyrethroid insecticide, used in agriculture, and one of the most common contaminants in freshwater aquatic systems. This paper reports an evaluation of the toxicity of CYP in the mosquitofish, exposed to two concentrations (0.2 ng/L and 6.25 ng/L). The result revealed a significant modulation in the activity of antioxidants enzymes, superoxide dismutase, catalase and decreased acetylcholinesterase after 7 days. Hydrogen peroxide (H2O2) and malondialdehyde levels remained elevated throughout the exposure duration. CYP causes gills and liver oxidative stress, modifying the antioxidant enzymes. Principal component analysis highlighted relationship between biomarkers in functional response. These findings suggest that exposure to CYP can lead to various antioxidant processes in the fish gills and liver.
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