Assessment of Bailing Capsule in the Treatment of Chronic Glomerulonephritis: A Meta-analysis

Abstract

The aim of the study is to provide evidence-based information for the efficacy, range of adaptation, dosage and course of treatment and adverse reactions for the treatment of chronic glomerulonephritis using Bailing capsule. Computer and manual retrieval was used to collect the clinical literature on treatment of chronic glomerulonephritis with Bailing capsule. A total of 661 patients (330 cases in the treatment group and 331 cases in the control group) in 8 reported studies were included as per inclusion criteria. RevMan 4.2 software was used to analyze the overall efficacy, the change of urine protein within 24 h before and after treatment, course of treatment, dosage, and adverse reactions. The total effect of Bailing capsule in the treatment of chronic glomerulonephritis was better than that in the control group. Compared to the control group, Bailing capsule exerted better control on urine protein without serious adverse reactions. There was a certain publication bias against the included cases. Bailing capsule brought urine protein from nephritis under control, but it is still necessary to make further investigation into the effect of Bailing capsule on different renal pathological changes of chronic glomerulonephritis, the best dosage and course of treatment.