Abstract
Splenomegaly is the disease commonly affecting normal anatomy and histology of spleen. It remains undetectable and worsens as the time passes and person suffers from stressful life. It leads as a consequence of many diseases. One of them important disease is Liver cirrhosis. In Ayurveda also relation of liver and spleen is depicted emphatically. Yakrita and Pleeha are described as Moolsthana of Raktvaha Strotasa and site of Raktadhara Kala and which are the important aspects of Ayurvedic Rachana Sharir. The facts regarding liver cirrhosis and splenomegaly are very much serious which has provoked us to think about to detail study of splenomegaly due to liver cirrhosis. There is no absolute treatment of splenomegaly till date. In Bhavprakasha, there is reference regarding Sharpunkha (Tephrosia Purpurea)that it is “Pleehashatru” showing that it might acts on the spleen and cures splenic disorders. But there is evidence base gap regarding efficacy of Sharpunkha on Splenomegaly. Kshara or Churna of Sharpunkha Panchanga are described as its useful preparations. There is no work done till date showing action of Sharpunkha Panchanga Kshara or Churna on Splenomegaly and there is deficit of study showing alteration in anatomy and histology of spleen affecting due to splenomegaly by using Sharpunkha. So it is needed to study effect of both Kshara and Churna separately and compare them so that we can use Panchanga Kshara or Panchanga Churna with more specificity. It can be a new modality in the field of Ayurvedic science to study effect of Sharpunkha Panchanga Kshara and Panchanga Churna on Splenomegaly showing changes in anatomy and histology of spleen affecting due to splenomegaly. Also with the help of that “Pleehghan Prabahva” and classical assert as “Pleehashatru” of Sharpunkha can be proven.
Highlights
Spleen is the largest lymphoid organ of the body. it is wedged shape organ having tetrahedral shape
Pharmaceutical Study: Preparation three different batches of Sharpunkha Panchanga Kshara and Churna will be done in order to establish its pharmacurtical standardization
Is the most common disease occurring as complication of liver cirrhosis
Summary
Spleen is the largest lymphoid organ of the body. it is wedged shape organ having tetrahedral shape. Nitroflubriprofen and Flubriprofen are used to treat portal hypertension causing splenomegaly [7] They may lead to hyperglycemia and increases the risk of heart block in patients with cardiac problem. That means it is used for diseases of spleen. He has mentioned that Sharpunkha is useful in Yakrit Vikar, PleehaVikar, Gulma, Vrana and VishaVikar. Considering these statements, it can be said that Sharpunkha might reduces the enlargement of spleen by showing action on it and can help in management of splenomegaly. This enlightens us to do this study that might show effect of Sharpunkha Churna and Kshara on splenomegaly
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