Abstract

This diagnostic study describes an online tool created with actual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus copy number data to help policy makers understand how pooled testing compares with single-sample testing in different populations.

Highlights

  • Policy makers are promoting pooled testing as a strategy to increase the number of people tested for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the coronavirus disease (COVID-19) pandemic, especially for population screening.[1,2] combining samples before testing brings trade-offs, such as decreasing the sensitivity and increasing the complexity of testing, that should be considered.We created an online tool using actual SARS-CoV-2 virus copy+ Invited Commentary

  • Number (VCN) data—the COVID19 Pool Tool—to help policy makers understand how pooled testing compares with single-sample testing in different populations

  • This diagnostic study was approved with a waiver of consent and Health Insurance Portability and Accountability Act authorization by the Duke Health institutional review board as part of retrospective SARS-CoV-2 test method comparison and validation studies

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Summary

Introduction

Policy makers are promoting pooled testing as a strategy to increase the number of people tested for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the coronavirus disease (COVID-19) pandemic, especially for population screening.[1,2] combining samples before testing brings trade-offs, such as decreasing the sensitivity and increasing the complexity of testing, that should be considered.We created an online tool using actual SARS-CoV-2 virus copy+ Invited Commentary.

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