Abstract

Objective: to investigate the application of continuous veno-venous hemodiafiltration (CVVHDF) in acute renal failure (ARF) after cardiac surgery. Methods: 30 patients with acute renal failure after cardiac surgery in xijing hospital from June 2011 to December 2013 were selected and treated with CVVHDF. The changes of Cr, BUN, electrolyte (K+, Na+, Cl-, etc.), HR, MAP, PaO2/FiO2, CVP were compared at 24 and 72 h before and after treatment using computer data analysis technology. Results: of the 30 patients, 26 survived and 4 died. Among them, the urine volume and renal function of the surviving patients returned to normal. Compared with before treatment, Cr, BUN, electrolyte (K+, Na+, Cl-, etc.) and HR were all significantly reduced, with statistically significant differences (P <0.05). The oxygenation index (PaO2/FiO2) and average arterial pressure (MAP) were significantly increased, while the central venous pressure (CVP) was significantly reduced, with statistically significant differences (P <0.05). Conclusion : CVVHDF is a safe and effective treatment and is worthy of clinical application.

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