Abstract

(1) Background: Appetite loss in older people, the ‘Anorexia of Aging’ (AA), is common, associated with under-nutrition, sarcopenia, and frailty and yet receives little attention. This review had two aims: describe interventions for AA and their effectiveness, and identify the methods of appetite assessment. (2) Methods: Study inclusion: participants aged ≥65, intervention for AA, and appetite assessment, any design, and comparator. Exclusion: studies on specific health cohorts. Searches in four databases with hand searching of references and citing works. Two researchers independently assessed eligibility and quality. (3) Results: Authors screened 8729 titles, 46 full texts. Eighteen articles were included describing nine intervention types: education (n = 1), exercise (n = 1), flavor enhancement (n = 2), increased meal variety (n = 1), mealtime assistance (n = 1), fortified food (n = 1), oral nutritional supplement (ONS) (n = 8), amino acids (n = 1), and medication (n = 2). Three studies evaluated combinations: education + exercise, ONS + exercise, and ONS + medication. Five intervention types exhibited favorable effects on appetite but in single datasets or not replicated. Appetite was assessed predominantly by Likert (n = 9), or visual analogue scales (n = 7). (4) Conclusions: A variety of interventions and methods of appetite assessments were used. There was a lack of clarity about whether AA or undernutrition was the intervention target. AA is important for future research but needs standardized assessment so that effectiveness of a range of interventions can be fully explored.

Highlights

  • The loss of appetite experienced by older people has been largely attributed to the aging process and is often termed the ‘anorexia of aging’ (AA) [1]

  • The nine different types of intervention for AA were broadly categorized into education, exercise, meal adjustments, supplementation (ONS, amino acid precursor, fortified food), medication and combinations

  • This review has focused on appetite assessment methods for older people in the context of an intervention

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Summary

Introduction

The loss of appetite experienced by older people has been largely attributed to the aging process and is often termed the ‘anorexia of aging’ (AA) [1]. AA has been linked to a number of important sequelae, predominantly due to poor oral intake and reduction in a variety of nutrients including protein, fiber, whole grains, fruits, and vegetables [3,4]. The consequences of AA include the development of subsequent undernutrition, immunosuppression, Nutrients 2019, 11, 144; doi:10.3390/nu11010144 www.mdpi.com/journal/nutrients. Nutrients 2019, 11, 144 and reduction in a variety of nutrients including protein, fiber, whole grains, fruits, and vegetables [3,4]. The consequences of AA include the development of subsequent undernutrition, immunosuppression, sarcopenia, and frailty (which can appetite reciprocally worsen appetite further). This sarcopenia, and frailty (which can reciprocally worsen further)

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