Abstract
With improvements in mortality in systemic lupus erythematosus(SLE), the health-related quality of life(HRQoL)of these patients is increasingly being recognized as an important outcome.Domains of HRQoL of particular importance to SLE patients include fatigue, pain, ability to study, independence, social and family life and learned helplessness.The MOS 36-item short from health survey(SF-36) currently appears to be the best available generic instrument for the assessment of HRQoL in SLE.It has been shown that SLE patients have poorer functional status than the general population.HRQoL in SLE patients has been improved by psycho-educational interventions including telephone counselling, a self-help course, group psychotherapy; therapies including biological agents, mycophenolate mo-fetil and a cholesterol- lowering diet.Additional research is needed to identify strategies which can improve HRQoL in SLE patients. Key words: Quality of life; Systemic lupus erythematosus; Intervention studies; Outcome assessment
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