Abstract

Background and objectivePulmonary hypertension is an assorted state that encompasses a spectrum of diseases and is categorized into five groups. The registries are necessary for the identification of risk factors, progression of the disease, outcomes, and effect of treatment strategies on the progression of the disease. The aim of this work was to identify different groups of PH identified at an Egyptian referral center and to compare the demographic and clinical characteristics of each group.Patients and methodsThis study included 132 patients who were diagnosed with a right heart catheter in the Chest Department, Kasr El-Aini Hospital, Faculty of Medicine, Cairo University, in the period from January 2017 to January 2019. Patients were classified into different groups, then received medical treatment accordingly. Demographic and clinical data were documented. Arterial blood gases, spirometry, and 6-minute walk test (6MWT) were performed.ResultsThe mean age of cases was (43.9±13.69) years; the majority of them were females (72.7%). More than half of the patients (57.5%) had pulmonary artery hypertension (PAH), while 22.7% and 18.3% had pulmonary hypertension due to chronic thrombo-embolic cause and lung cause respectively. The 1-year survival rate was 81.8%.ConclusionsThe results of the study showed female predominance, the PAH type was the commonest, and the overall 1-year survival rate was 81.8%.

Highlights

  • Background and objectivePulmonary hypertension is an assorted state that encompasses a spectrum of diseases and is categorized into five groups

  • More than half of the patients (57.5%) had pulmonary artery hypertension (PAH), while 22.7% and 18.3% had pulmonary hypertension due to chronic thrombo-embolic cause and lung cause respectively

  • The definition of pulmonary hypertension (PH) is elevated mean pulmonary artery pressure more than 25mmHg at right heart catheterization (RHC). It is classified into five different groups: group 1, pulmonary arterial hypertension (PAH); group 2, PH due to left heart disease (LHD); group 3, PH due to lung disease; group 4, chronic thromboembolic PH (CTEPH); and group 5, PH with unclear multifactorial mechanisms [1]

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Summary

Introduction

Background and objectivePulmonary hypertension is an assorted state that encompasses a spectrum of diseases and is categorized into five groups. The definition of pulmonary hypertension (PH) is elevated mean pulmonary artery pressure (mPAP) more than 25mmHg at right heart catheterization (RHC) It is classified into five different groups: group 1, pulmonary arterial hypertension (PAH); group 2, PH due to left heart disease (LHD); group 3, PH due to lung disease; group 4, chronic thromboembolic PH (CTEPH); and group 5, PH with unclear multifactorial mechanisms [1]. It is a severe, progressive disease associated with significant morbidity and mortality [2]. From that point of view; the current study brings to light the Elshazly et al Egypt J Bronchol (2021) 15:48

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