Abstract

Assessing the relation between alcohol consumption and risk of disease and mortality \u2013 reply

Highlights

  • The Kailuan study is located in Hebei Province, where 95.8% of the population are Han Chinese, according to the 2010 Population Census of China [3]

  • Because the proportion of ethnic minorities in this population is small and no strong evidence supports an association between specific ethnic groups in Hebei Province and different disease risks, we did not adjust for ethnicity in our study

  • * Correspondence: xxg14@psu.edu 1Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA Full list of author information is available at the end of the article the self-report alcohol intake has previously been validated against blood high-density lipoprotein cholesterol concentration in our cohort [6]

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Summary

Introduction

In response to our study on the association between alcohol consumption and risk of cardiovascular disease, cancer, and mortality [1], Alam et al raised concerns on three specific aspects of the study, including confounding factors, exposure assessment, and the follow-up duration. All participants in our study are Chinese. The reference paper cited by Alam et al only compared differentials in heart disease mortality across black, white, Hispanic, and Asian populations [2], it cannot translate directly to our study.

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