Abstract

Objective: To assess the Influence of Comfortable nursing for therapeutic plasma exchange treatment of severe hepatitis patient. Methods: 92 patients who were diagnosed as severe hepatitis from July 2017 to July 2018 were invited to join our study. We were randomly assigned the participants to the control group (n = 46) and the intervention group (n = 46), control group receive traditional nursing services and intervention group had additional comfortable care services. our researchers collected anxiety information and depression information by questionnaires which include Self-Rating Anxiety Scale (SAS) and Self-rating depression scale (SDS). Additionally, patient satisfaction and comfort level was collected by other questionnaires. Result: In the satisfaction research, intervention group had higher score of satisfaction assessment than that of control group [45 (97.8%) vs 39 (84.8%)]. In comfort level research, the intervention group had more 0 level assessment in our research result (n = 23). In result of SAS and SDS, the intervention group had greater improvement than that of control group in the SDS and SAS as the result of intervention group lowered scores even more. Conclusion: the comfortable care improve the outcome of therapeutic plasma exchange on severe hepatitis patient. In particular, the comfortable care greatly improve anxiety status and comfort level in the treatment process of therapeutic plasma exchange.

Highlights

  • Therapeutic plasma exchange (TPE) is a extracorporeal technique

  • According to American Society for Apheresis guidelines, over 30 diseases may be treated with TPE [3]

  • The comfortable care improves the outcome of therapeutic plasma exchange on severe hepatitis patient

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Summary

Introduction

Therapeutic plasma exchange (TPE) is a extracorporeal technique. Based on how it works, on the one hand, patient's plasma is separated from whole blood and removed. On the another hand, the cellular blood components and replacement fluid are returned to the patient. Both kinds of work are done simultaneously to have a therapeutic effect [1]. The rational for TPE is the removal of a pathological substance in plasma that is responsible for the disease, i.e. autoantibodies, immune complexes, cryoglobulins, toxins or lipids [4]. TPE could be seen by many healthcare professionals as a non-selective unsophisticated procedure

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