Abstract
The aim of the present study was to assess the effect of nano-biphasic calcium phosphate (nanoBCP) scaffolds on acute alveolar bone defects in beagle dogs by micro-computed tomographic imaging (μCT). Alveolar bone defects were surgically created bilaterally at the buccal aspects of the upper second premolars in four beagle dogs. After root conditioning with ethylenediaminetetraacetate (EDTA), nanoBCP was randomly filled in the defects and nothing was put into the contralateral defects as controls. Dogs were killed at the 24th weeks. Specimens were scanned and reconstructed though μCT. The results revealed that much new alveolar bone formed in the defects in the nanoBCP groups while no new alveolar bone formed in the controls. The present results indicate that PBCP may enhance alveolar bone regeneration in acute-type labial dehiscence defects.
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