Assessing Severity in Common variable immune deficiency (CVID) using the "Ameratunga Score- AS"

Abstract

A proportion of patients with CVID evolves with a prominent T cell defect leading to a more severe phenotype with opportunistic infections, being considered by some experts as Late Onset Combined Immunodeficiency (LOCID). The aim of the study was to assess the severity of CVID using the “AS”, which focuses mainly on cumulative damage to organs such as result of infections, autoimmunity or inflammation.