Abstract

Abstract Aging is a universal human experience that looms large in popular and commercial culture. It can be difficult for patients and providers alike to sort fact from unproven plausibility and from potentially harmful fiction. Geroscience is an emerging field, and while some interventions involve repurposed or over-the-counter drugs with early clinical data, it is important to note that none yet have a specific aging-related indication and none have a consensus recommendation for clinical use in an aging context. Even highly plausible links to mechanisms of aging do not ensure that an intervention will be effective or risk-free, and not all purported therapies align with preclinical science. Finally, some purported therapies fall into potentially problematic regulatory gaps. With all of these considerations in mind, attendees will gain insights into applying their existing skills to evaluate this field, and new tools for critically evaluating geroscience literature to assist in patient-centered decision making.

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