Abstract
Assessing Cellular Responses in Sepsis
Highlights
It is clear that sepsis therapies need to be adapted to the individual patient rather than directed at a general diagnosis of ‘sepsis’
By its induced immunosuppression is like defining a problem by its consequences, and such a test is perhaps applied too late to be of use in facilitating early patient management
Cellular reprogramming may be more helpful to estimate the risk of nosocomial infection than for sepsis diagnosis (Conway Morris et al, 2013), and future studies should evaluate these changes prospectively in patients who are not infected at the time of hospital admission
Summary
It is clear that sepsis therapies need to be adapted to the individual patient rather than directed at a general diagnosis of ‘sepsis’. By its induced immunosuppression is like defining a problem by its consequences, and such a test is perhaps applied too late to be of use in facilitating early patient management. Cellular reprogramming may be more helpful to estimate the risk of nosocomial infection than for sepsis diagnosis (Conway Morris et al, 2013), and future studies should evaluate these changes prospectively in patients who are not infected at the time of hospital admission.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
