Abstract
Structural Biology The biogenesis of ribosomes is a multistep process facilitated by assembly factors. Saurer et al. provided structural information on the maturation process of the mitochondrial ribosome, or mitoribosome, in the parasitic protozoan Trypanosoma brucei (see the Perspective by Karbstein). Cells evolved a dedicated machinery for maturation of the small subunit of the mitoribosome, including the formation of three distinct and well-structured assembly intermediates. Comparison of intermediates and the mature mitoribosome reveals how assembly factors and ribosomal proteins work together to fold and stabilize ribosomal RNA. Science , this issue p. [1144][1]; see also p. [1077][2] [1]: /lookup/doi/10.1126/science.aaw5570 [2]: /lookup/doi/10.1126/science.aay7771
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