Abstract
<p indent="0mm">In the field of micro and nano optics, transparent dielectric microspheres and living biological cells have attracted more and more attention due to their optical imaging capabilities. However, it is difficult to integrate them directly onto optical systems because of their size and bioactivity limitations. Although multi-physics field methods based on optical tweezers and acoustic tweezers can manipulate microspheres and cells for imaging, they tend to have specific requirements for imaging samples. Here, we proposed a method for the preparation of microsphere/cellular lens array modules based on maskless lithography. Natural sedimentation principle is utilized to form microlens arrays by assembling SiO<sub>2</sub> microspheres and MCF-7 cells on the hydrogel microporous module. The experimental and simulation results show that the SiO<sub>2</sub> microsphere array embedded in the hydrogel still maintains its super-resolution imaging capability, and the MCF-7 cells can achieve the image magnification. As a result of the arrayed imaging, a larger viewing field can be obtained than that of individual microspheres or cells. The modular imaging method proposed in this paper is expected to be applied in the field of biophotonic devices and <italic>in vivo</italic> optical imaging.
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