Abstract

The adsorption behavior of the antihypertensive and antianginal agent amlodipine besylate onto a Hanging Mercury Dropping Electrode (HMDE) was explored by square wave and cyclic voltammetry. The drug accumulat ed at HMDE and a well-defined peak was obtained at �1.73V versus Ag/AgCl (saturated KCl) in phosphate buffer at pH 7. A validated simple, rapid and sensitive square -wave voltammetric procedure was described for direct determination of the authentic cited drug. The optimum procedure conditions were accumulation potential E

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